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Chang Z Zhu Selected Research

A-836339

1/2011Central and peripheral sites of action for CB₂ receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats.
1/2009Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imaging.

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Chang Z Zhu Research Topics

Disease

18Neuralgia (Stump Neuralgia)
04/2014 - 12/2002
16Hyperalgesia
01/2014 - 12/2002
11Pain (Aches)
04/2014 - 12/2004
7Postoperative Pain
10/2011 - 12/2002
4Inflammation (Inflammations)
11/2018 - 07/2005
3Chronic Pain
04/2014 - 12/2002
2Proteinuria
11/2018 - 10/2016
2Fibrosis (Cirrhosis)
11/2018 - 12/2017
2Hypersensitivity (Allergy)
02/2012 - 12/2004
1Kidney Diseases (Kidney Disease)
11/2018
1Peritonitis
03/2010
1Neurologic Manifestations (Neurological Manifestations)
03/2010
1Edema (Dropsy)
12/2004
1Necrosis
10/2004
1Brain Ischemia (Cerebral Ischemia)
10/2004
1Hypoglycemia (Reactive Hypoglycemia)
10/2004
1Infarction (Infarctions)
10/2004
1Ischemia
10/2004
1Peripheral Nerve Injuries
12/2003
1Visceral Pain
12/2002
1Acute Pain
12/2002

Drug/Important Bio-Agent (IBA)

8Analgesics (Analgesic Drugs)IBA
04/2014 - 12/2004
8Freund's AdjuvantIBA
04/2014 - 12/2002
5CarrageenanIBA
10/2011 - 12/2003
3Capsaicin (Zostrix)FDA Link
02/2012 - 07/2005
3A-317491IBA
09/2005 - 12/2002
2Biomarkers (Surrogate Marker)IBA
11/2018 - 04/2014
2Messenger RNA (mRNA)IBA
11/2018 - 01/2011
2N2- methyl- N- ((2- (4- (trifluoromethyl)phenyl)octahydrocyclopenta(c)pyrrol- 4- yl)leucinamideIBA
04/2014 - 01/2014
2CannabinoidsIBA
01/2011 - 01/2009
2A-836339IBA
01/2011 - 01/2009
2Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
02/2008 - 03/2005
2Glutamic Acid (Glutamate)FDA Link
02/2008 - 12/2004
2Vincristine (Oncovin)FDA LinkGeneric
12/2006 - 12/2004
2Naloxone (Narcan)FDA LinkGeneric
02/2006 - 09/2005
2Formaldehyde (Formol)FDA Link
09/2005 - 12/2004
2NucleotidesIBA
12/2003 - 12/2002
1CalbindinsIBA
11/2018
1ClusterinIBA
11/2018
1Cystatin CIBA
11/2018
1CreatinineIBA
11/2018
1AdenineFDA LinkGeneric
11/2018
1Extracellular Matrix ProteinsIBA
12/2017
1beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA
10/2016
1Adenosine (Adenocard)FDA LinkGeneric
10/2016
1Purine NucleosidesIBA
10/2016
1Mitogen-Activated Protein Kinase 3IBA
04/2014
1N-Type Calcium Channels (N-Type Calcium Channel)IBA
09/2013
1Neurotransmitter Agents (Neurotransmitter)IBA
02/2012
1A-1048400IBA
02/2012
1Acetates (Acetic Acid Esters)FDA Link
10/2011
13- (3- (pyridine- 3- yl)- 1,2,4- oxadiazol- 5- yl)benzonitrileIBA
10/2011
15-(2-azetidinylmethoxy)-2-chloropyridineIBA
10/2011
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
10/2011
1salicylhydroxamic acid (SHAM)IBA
01/2011
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
01/2011
1AM 1241IBA
01/2011
1Histamine (Histamine Dihydrochloride)FDA Link
03/2010
1ZymosanIBA
03/2010
11- ((5- chloro- 1H- indol- 2- yl)carbonyl)- 4- methylpiperazineIBA
03/2010
1mu Opioid Receptors (mu Opioid Receptor)IBA
01/2009
1CB2 Cannabinoid ReceptorIBA
01/2009
1cyclopropanecarboxylic acidIBA
01/2009
1AmidesIBA
01/2009
1A-889425IBA
12/2008
1PiperazineIBA
06/2008
1furanIBA
06/2008
1Lamotrigine (Lamictal)FDA LinkGeneric
06/2008
1Mexiletine (Mexitil)FDA LinkGeneric
06/2008
1Sodium Channel BlockersIBA
06/2008
19- dimethylamino- 3- (4- methylphenyl)- 3H- 5- thia- 1,3,6- triazafluoren- 4- oneIBA
02/2008
19- dimethylamino- 3- cycloheptyl- 3H- 5- thia- 1,3,6- triazafluoren- 4- oneIBA
02/2008
19- dimethylamino- 3- (4- ethylphenyl)- 3H- 5- thia- 1,3,6- triazafluoren- 4- oneIBA
02/2008
1A-841720IBA
02/2008
1(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)- 2,2- dimethylpropyl)- 2- (3,4- dimethoxyphenyl)acetamide)IBA
12/2006
1Purinergic P2X7 ReceptorsIBA
12/2006
1acetamideIBA
12/2006
1Carboxylic AcidsIBA
11/2006
1LigandsIBA
11/2006
1HeptanesIBA
11/2006
12-phenylglycineIBA
11/2006
1Calcium Channels (Calcium Channel)IBA
11/2006
1Pregabalin (Lyrica)FDA Link
11/2006
1Gabapentin (Neurontin)FDA LinkGeneric
11/2006
1Morphine (MS Contin)FDA LinkGeneric
02/2006
1Opioid Analgesics (Opioids)IBA
09/2005
1Vasopressin Receptors (Arginine Vasopressin Receptor)IBA
07/2005
1Urea (Carbamide)FDA LinkGeneric
07/2005
11- isoquinolin- 5- yl- 3- (4- trifluoromethyl- benzyl)- ureaIBA
07/2005
1Acetic Acid (Vinegar)FDA LinkGeneric
12/2004
1Insulin (Novolin)FDA Link
10/2004
1Blood Glucose (Blood Sugar)IBA
10/2004
1Neuroprotective AgentsIBA
10/2004
1Glucose (Dextrose)FDA LinkGeneric
10/2004

Therapy/Procedure

8Ligation
01/2014 - 12/2002
3Oral Administration
10/2016 - 07/2005
1Pain Management
12/2004
1Injections
12/2003